反应详情

A suspension of the above ester (0.07 g, 0.19 mmol) in 1 N sodium hydroxide (1 mL) was stirred at ambient temperature for 12 h. Upon acidification of the reaction mixture with glacial acetic acid, a solid precipitated. This solid was collected by filtration and dried to give 0.05 g (75%) of the title compound as a white solid, mp 220-221° C.

1. customUpon acidification of the reaction mixture with glacial acetic acid, a solid precipitated
2. filtrationThis solid was collected by filtration
3. customdried