Butylamine → N-n-butyl-4-acetamidobenzamide

HRID 1635571노트

반응식

HRID 1635571 반응식
[N+](C1C=C[C:7]([C:8](Cl)=[O:9])=CC=1)([O-])=O.C(N)CCC.[CH2:18]([NH:22][C:23](=[O:33])[C:24]1[CH:29]=[CH:28][C:27]([N+:30]([O-])=O)=[CH:26][CH:25]=1)[CH2:19][CH2:20][CH3:21]>>[CH2:18]([NH:22][C:23](=[O:33])[C:24]1[CH:29]=[CH:28][C:27]([NH:30][C:8](=[O:9])[CH3:7])=[CH:26][CH:25]=1)[CH2:19][CH2:20][CH3:21]

참가 물질

4

반응물 3

HCID 8007ButylamineHCID 85024-Nitrobenzoyl chlorideHCID 347929N-butyl-4-nitrobenzamide

생성물 1

HCID 2425673N-n-butyl-4-acetamidobenzamide

실험 절차

The method of Example 3 is repeated using 4-nitrobenzoyl chloride and n-butyl amine in the amidation step. This yields N-n-butyl-4-nitrobenzamide (CPI1045).

출처 및 근거

ORD 기록
ord-a8d1b7f637974890915ee37eb3c58683
출처 데이터셋
uspto-grants-2003_01
특허 번호
US06509378B2

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