HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 6,7-Dimethoxy-1,2-dimethyl-3,4-dihydroisoquinolin-2-ium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 3,4-Dihydro-6,7-dimethoxy-1-methylisoquinoline | HCID 22652 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 6,7-Dimethoxy-1,2-dimethyl-3,4-dihydroisoquinolin-2-ium iodide | HCID 13419042 | 95% |
Reaction Steps
To a stirred solution of 1-methyl-6,7-dimethoxy-3,4-dihydroisoquinoline in acetone was added methyl iodide and the reaction mixture was stirred at room temperature for 16 hours. A bright yellow precipitate formed. The by-products and methyl iodide were removed in vacuo to afford the desired compound in 95% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06509467B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-1ee6a61745d54953825ea293f9a28afd |
| Source note | uspto-grants-2003_01 |