関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,3,5-Trichlorobenzene | HCID 7950 | — |
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 3,5-Dichlorophenylhydrazine | HCID 600469 | 60% |
反応手順
A mixture of 1,3,5-trichlorobenzene (2.53 g), hydrazine hydrate (3.48 g, 5 molar equivalents) and pyridine (12 ml) was heated in an autoclave (purged with argon) for 6 hours at 180° C. The mixture was cooled, the excess hydrazine decanted and the organic phase evaporated in vacuo to give the title compound in 60% yield. It was shown that 65% of the starting material had been consumed, thus indicating that the reaction had occurred with high selectivity.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06509503B1 |
|---|
| 出典データセット | uspto-grants-2003_01 |
|---|
| ORD ID | ord-3e6a2dccd2424f91bb0356d383f5ee0e |
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| 出典メモ | uspto-grants-2003_01 |
|---|
