3-Nitrophenol → 3-(2-Morpholin-4-ylethoxy)aniline

HRID 1635798Notes

Reaction equation

HRID 1635798 reaction equation
Cl.Cl[CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1.[N+:11]([C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1)([O-])=O>>[NH2:11][C:14]1[CH:15]=[C:16]([CH:17]=[CH:18][CH:19]=1)[O:20][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1

Participants

3

Reactant 2

HCID 111373-NitrophenolHCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)

Product 1

HCID 64866163-(2-Morpholin-4-ylethoxy)aniline

Procedure

By the method of examples 2 and 3, 4-(2-chloroethyl)morpholine hydrochloride and 3-nitrophenol were converted into the title compound.

Sources & evidence

ORD record
ord-3571c9c5e7f64d1b86307f429e77304c
Source dataset
uspto-grants-2003_01
Patent number
US06511980B2

Reaction notes

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