HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 9952978, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 9798048 | HCID 9798048 | — |
| Reactant | HCID 178418800 | HCID 178418800 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9952978 | HCID 9952978 | 32.1% |
Reaction Steps
In the manner of Example 9's Method 1, employing (2-chloro-4-fluorophenyl)-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone (1.0 g), 60% sodium hydride in oil (0.3 g, degreased with hexane), 4-methylimidazole (0.48 g), and dimethylformamide (25 ml), the title compound (0.38 g) was obtained as an amorphous solid, MS, m/z: 403.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06511974B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-f1188c2f5131488d881742aa45e0266e |
| Source note | uspto-grants-2003_01 |