HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylpyrazole → HCID 9824424, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylpyrazole | HCID 3406 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 9865339 | HCID 9865339 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9824424 | HCID 9824424 | 66.7% |
Reaction Steps
In the manner of Example 9's Method 1, employing (2-chloro-4-trifluoromethyl-pyrimidin-5-yl)-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepin-10-yl)-methanone (0.98 g), 60% sodium hydride in oil (0.15 g), 4-methylpyrazole (0.42 g) and dimethylformamide (25 ml), the title compound (0.73 g) was obtained as a crystalline solid, m.p. 214-217° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06511974B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-442f784996344dbd9edc43ba80499718 |
| Source note | uspto-grants-2003_01 |