HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-(1H-Imidazol-1-yl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(1-Imidazolyl)benzoic Acid | HCID 736529 | — |
| Product | 4-(1H-Imidazol-1-yl)benzoyl chloride | HCID 14537427 | — |
Reaction Steps
A suspension of 4-(imidazol-1-yl)benzoic acid (0.90 g) in thionyl chloride (2.0 ml) was heated on a steam bath under argon for one hour. Evaporation of the volatile material under reduced pressure afforded a residue which crystallized upon the addition of hexane to yield the 4-(imidazol-1-yl)benzoyl chloride as the hydrochloride salt (1.17 g), m.p. 242-247° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06511974B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-5af3c371906c46e9bd9695ac64130e8e |
| Source note | uspto-grants-2003_01 |