Water → HCID 18673950, compound

HRID 1635980Notes

Reaction equation

HRID 1635980 reaction equation
[C:1]([C:3]1[CH:4]=[CH:5][C:6]([O:9][C:10]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:11]=2[CH2:12][CH2:13][C:14]3=[O:19])=[N:7][CH:8]=1)#N.[OH2:20]>C(O)=O.[Ni]>[CH:1]([C:3]1[CH:4]=[CH:5][C:6]([O:9][C:10]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:11]=2[CH2:12][CH2:13][C:14]3=[O:19])=[N:7][CH:8]=1)=[O:20]

Participants

5

Reactant 2

HCID 962WaterHCID 18673869HCID 18673869, compound

Product 1

HCID 18673950HCID 18673950, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 284Formic AcidSolvent

Procedure

To a solution prepared by suspending 4.6 g of 4-[(5-cyano-2-pyridinyl)oxy]-1-indanone obtained in Reference Example 59 in 4.4 ml of water and 11 ml of formic acid, 2.6 g of raney nickel was added at 60° C.

Workup

  1. customTo a solution prepared

Sources & evidence

ORD record
ord-1dd9fe0a94c64a889f16619e293f5f4e
Source dataset
uspto-grants-2003_01
Patent number
US06511995B1

Reaction notes

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