4-(Trifluoromethyl)benzoic acid → HCID 18673933, compound

HRID 1635990Notes

Reaction equation

HRID 1635990 reaction equation
FC(F)(F)C1C=C[C:6]([C:7](O)=[O:8])=[CH:5]C=1.[O:14]([C:21]1[N:26]=[CH:25][C:24]([NH2:27])=[CH:23][CH:22]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[NH2:27][C:24]1[CH:23]=[CH:22][C:21]([O:14][C:15]2[CH:16]=[CH:17][CH:18]=[C:19]3[C:20]=2[CH2:5][CH2:6][C:7]3=[O:8])=[N:26][CH:25]=1

Participants

3

Reactant 2

HCID 99664-(Trifluoromethyl)benzoic acidHCID 2128566-Phenoxy-3-pyridinamine

Product 1

HCID 18673933HCID 18673933, compound

Procedure

According to the same manner as that described in Example 1 except for using an equimolar amount of 4-(trifluoromethyl)benzoic acid in place of 3,4-dichlorobenzoic acid and using an equimolar amount of 6-phenoxy-3-pyridinylamine obtained in Reference Example 32 in place of 4-[(5-amino-2-pyridinyl)oxy]-1-indanone, the reaction was carried out to obtain. the titled compound.

Sources & evidence

ORD record
ord-d3027645340a4b02ba49cc9fc8b81caa
Source dataset
uspto-grants-2003_01
Patent number
US06511995B1

Reaction notes

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