HCID 86758816, compound → HCID 86758815, compound

Participants

Reaction Steps

The reaction takes place analogously to the procedure described in Example 30 starting from ethyl 2-{2-[2-(4-amidinophenyl)-ethyl]-1-methyl-benzimidazol-5-yl-carbonyl-(methylamino)}-3-(4-amidinophenyl)-propionate (Example 29, 1.7 mmol). The product is obtained by crystallisation from dichloromethane/methanol. Yield: >90%; melting point: 255° C.; mass: calc.: [525], found: [M+H]+ 526; 1H-NMR (250 MHz, DMSO-d6): δ [ppm]=10.20 (1H, s, COOH); 8.61 (1H, s, HCOOH); 8.09-6.77 (17H, m, 2 C(═NH)NH2, aryl-H); 5.37 (1H, m, N—CH—); 3.78 (3H, s, aryl-N—CH3); 3.33 (4H, s, aryl-CH2—CH2—); 2.98 (3H, s, CO—N—CH3).

Provenance & Evidence