HCID 86586544, compound → HCID 10291017, compound

HRID 1636070Notes

Reaction equation

HRID 1636070 reaction equation
C([O:8][NH:9][C:10](=[O:32])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][O:18][C:19]1[C:31]2[C:30]3[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=3)[NH:24][C:23]=2[CH:22]=[CH:21][CH:20]=1)C1C=CC=CC=1>[Pd]>[OH:8][NH:9][C:10](=[O:32])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][O:18][C:19]1[C:31]2[C:30]3[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=3)[NH:24][C:23]=2[CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 1

HCID 86586544HCID 86586544, compound

Product 1

HCID 10291017HCID 10291017, compoundYield 46.2%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

In a manner anologous to that of example 1(c), 8-(9H-Carbazol-4-yloxy)-octanoic acid benzyloxyamide (300 mg, 0.7 mmol) was hydrogenated in the presence of palladium on barium sulfate to give the title compound (110 mg) in 46% yield as an amorphous solid. MS (M−H+)=339.

Sources & evidence

ORD record
ord-b4d830fccc0f4568bdf64db7cd7b2ea3
Source dataset
uspto-grants-2003_01
Patent number
US06512123B2

Reaction notes

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