HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dimethylglutaric acid → HCID 53886375, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dimethylglutaric acid | HCID 97870 | — |
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 53886375 | HCID 53886375 | 66.1% |
Reaction Steps
Using General Procedure A with 6.05 g (25 mmol) D-Proline benzyl ester hydrochloride and 2.0 g (12.5 mmol) 2,4-dimethylglutaric acid afforded, after flash chromatography (EtOAc), 4.3 g (64%) of the title compound as a light yellow oil. MS m/e (%): 535 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06512001B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-c969a8c7501342a58e0b2b52bd55274a |
| Source note | uspto-grants-2003_01 |