HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethylsuccinic acid → HCID 54106993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethylsuccinic acid | HCID 11848 | — |
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 54106993 | HCID 54106993 | 69% |
Reaction Steps
Using General Procedure A with 2.0 g (8.2 mmol) D-Proline benzyl ester hydrochloride and 600 mg (4.1 mmol) 2,3-dimethylsuccinic acid afforded, after flash chromatography (EtOAc), 1.45 g (69%) of the title compound as a colorless oil. MS m/e (%): 521 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06512001B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-cf9c05d719544a8fa8d0acc8f77c2711 |
| Source note | uspto-grants-2003_01 |