HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isophthalic Acid → HCID 53657616, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isophthalic Acid | HCID 8496 | — |
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 53657616 | HCID 53657616 | 72.1% |
Reaction Steps
Using General Procedure A with 5.8 g (24.0 mmol) D-Proline benzyl ester hydrochloride and 2.0 g (12.0 mmol) benzene-1,3-dioic acid afforded, after flash chromatography (EtOAc), 4.68 g (72%) of the title compound as a yellow oil. MS m/e (%): 558 (M+NH4+, 100), 541 (M+H+, 90).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06512001B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-6dfd68b96de1402286f52230ec786df8 |
| Source note | uspto-grants-2003_01 |