HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13124491, compound → HCID 15428308, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13124491 | HCID 13124491 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 15428308 | HCID 15428308 | — |
Reaction Steps
(3S, 4S)-3-benzyloxycarbonylamino-4-acetoxy-azetidin-2-one (912 mg, 3.28 mmol) is hydrogenated with 1 g of 10% palladium on activated carbon in 35 ml of ethyl acetate at 50 psi hydrogen pressure at room temperature for 1.5 hours. After removal of catalyst by filtration, desubstitution (3S,4S)-3-amino-4-acetoxy-azetidin-2-one in ethyl acetate is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034077 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-61156683bc2e4979b0ff513a981f16ed |
| Source note | uspto-grants-2000_03 |