HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-[2-(N-Carbobenzoxy-4-O-benzyl-L-aspartyl-D-alanyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-dodecyl-dodecanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartate | HCID 47602 | — |
| Reactant | N-(2D-alanyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-dodecyl-dodecanamide | HCID 131721233 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | N-[2-(N-Carbobenzoxy-4-O-benzyl-L-aspartyl-D-alanyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-dodecyl-dodecanamide | HCID 131721715 | 63% |
Reaction Steps
from N-(2D-alanyl-amino-2-deoxy-β-D-glucopyranosyl)-N-dodecyl-dodecanamide and N-carbobenzoxy-4-O-benzyl-L-aspartic acid. Yield 63%. Rf 0.57 (dichloromethane/methanol/conc. ammonia 15:1:0.1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034055 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-cac57bc6e2ee42d4a931898e53ff28cb |
| Source note | uspto-grants-2000_03 |