HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(Benzyloxycarbonyl)-L-serine → N-[2-(N-Carbobenzoxy-L-seryl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-dodecanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(Benzyloxycarbonyl)-L-serine | HCID 100310 | — |
| Reactant | N-(2-glycyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-tetradecyl-dodecanamide | HCID 131721235 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[2-(N-Carbobenzoxy-L-seryl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-dodecanamide | HCID 131721239 | 76% |
Reaction Steps
from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-tetradecyl-dodecanamide and N-carbobenzoxy-L-serine. Yield 76%. [α]D =+20.3° (c=0.89, dichloromethane). m.p. 87-89°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034055 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-e34557ed20084340812fdd2d2cf91dd9 |
| Source note | uspto-grants-2000_03 |