HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((Phenylmethoxy)carbonyl)-L-alanyl-L-alanine → N-[2-(N-Carbobenzoxy-L-alanyl-L-alanyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-dodecanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((Phenylmethoxy)carbonyl)-L-alanyl-L-alanine | HCID 7009583 | — |
| Reactant | N-(2-glycyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-tetradecyl-dodecanamide | HCID 131721235 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-[2-(N-Carbobenzoxy-L-alanyl-L-alanyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-dodecanamide | HCID 131721244 | 70% |
Reaction Steps
from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-tetradecyl-dodecanamide and N-carbobenzoxy-L-alanyl-L-alanine. Yield 70%. [α]D =+10.3° (c=0.92, tetrahydrofuran). m.p. 99-100°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034055 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-a96067869acb4841a3a0081842c5231f |
| Source note | uspto-grants-2000_03 |