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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1636262Generated: October 30, 2026

2-(2-{[(Tert-butoxy)carbonyl]amino}acetamido)acetic acid → N-[2-(N-tert-Butyloxycarbonyl-glycyl-glycyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-oleamide

https://huagongshe.com/reaction/1636262

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-{[(Tert-butoxy)carbonyl]amino}acetamido)acetic acidHCID 333466—
ReactantN-(2-glycyl-amino-2-deoxy-beta-glucopyranosyl)-N-tetradecyl-oleamideHCID 131721258—
SolventTetrahydrofuranHCID 8028—
ProductN-[2-(N-tert-Butyloxycarbonyl-glycyl-glycyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-oleamideHCID 13172172274%

Reaction Steps

from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-tetradecyl-oleamide and N-tert-butyloxycarbonyl-glycyl-glycine. Yield 74%. [α]D =+14.2° (c=1.00, tetrahydrofuran).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06034055
Source datasetuspto-grants-2000_03
ORD IDord-363a78c64b214133a0279bea974045eb
Source noteuspto-grants-2000_03