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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1636271Generated: October 30, 2026

(3S)-4-(tert-butoxy)-3-{[(tert-butoxy)carbonyl]amino}-4-oxobutanoic acid → N-[2-(N-tert-Butyloxycarbonyl-O-tert-butyl-L-aspartyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-octadecyl-oleamide

https://huagongshe.com/reaction/1636271

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-4-(tert-butoxy)-3-{[(tert-butoxy)carbonyl]amino}-4-oxobutanoic acidHCID 7010517—
ReactantN-(2-glycyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-octadecyl-oleamideHCID 131721266—
SolventDichloromethaneHCID 6344—
ProductN-[2-(N-tert-Butyloxycarbonyl-O-tert-butyl-L-aspartyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-octadecyl-oleamideHCID 13172172488%

Reaction Steps

from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-octadecyl-oleamide and N-tert-butyloxycarbonyl-O-tert-butyl-L-aspartic acid. Yield 88%. [α]D =+13.8° (c=0.93, dichloromethane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06034055
Source datasetuspto-grants-2000_03
ORD IDord-286bd0568f224b57bd5c2f012d0b575c
Source noteuspto-grants-2000_03