HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-{[(Tert-butoxy)carbonyl]amino}acetamido)acetic acid → N-[2-(N-tert-Butyloxycarbonyl-glycyl-glycyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-octadecyl-oleamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-{[(Tert-butoxy)carbonyl]amino}acetamido)acetic acid | HCID 333466 | — |
| Reactant | N-(2-glycyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-octadecyl-oleamide | HCID 131721266 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[2-(N-tert-Butyloxycarbonyl-glycyl-glycyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-octadecyl-oleamide | HCID 131721725 | 81% |
Reaction Steps
from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-octadecyl-oleamide and N-tert-butyloxycarbonyl-glycyl-glycine. Yield 81%. [α]D =+15.0° (c=0.94, dichloromethane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034055 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-e657ca7817b5416197eadb914a6746d7 |
| Source note | uspto-grants-2000_03 |