HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((1,1-Dimethylethoxy)carbonyl)-L-alanyl-L-alanine → N-[2-(N-tert-Butyloxycarbonyl-L-alanyl-L-alanyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N octadecyl-oleamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((1,1-Dimethylethoxy)carbonyl)-L-alanyl-L-alanine | HCID 6992569 | — |
| Reactant | N-(2-glycyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-octadecyl-oleamide | HCID 131721266 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[2-(N-tert-Butyloxycarbonyl-L-alanyl-L-alanyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N octadecyl-oleamide | HCID 131721265 | 55% |
Reaction Steps
from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-octadecyl-oleamide and N-tert-butyloxycarbonyl-L-alanyl-L-alanine. Yield 55%. [α]D =+10.3° (c=0.85, dichloromethane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034055 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-72d36cd20f904910825f8b28530b54af |
| Source note | uspto-grants-2000_03 |