3-Oxooctanoate → N-tert.-Butyl-4-(4,5-dihydro-3-propyl-5-oxo-1H-pyrazol-1-yl)-benzenesulfonamide

HRID 1636340Notes

Reaction equation

[C:1]([NH:5][S:6]([C:9]1[CH:14]=[CH:13][C:12]([NH:15][NH2:16])=[CH:11][CH:10]=1)(=[O:8])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:17]([CH2:19][CH2:20][CH2:21][C:22](CC([O-])=O)=[O:23])[CH3:18]>>[C:1]([NH:5][S:6]([C:9]1[CH:10]=[CH:11][C:12]([N:15]2[C:22](=[O:23])[CH2:21][C:20]([CH2:19][CH2:17][CH3:18])=[N:16]2)=[CH:13][CH:14]=1)(=[O:8])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 178046443-Oxooctanoate

HCID 19351350N-tert.-butyl-4-hydrazinobenzenesulfonamide

Product 1

HCID 19351352N-tert.-Butyl-4-(4,5-dihydro-3-propyl-5-oxo-1H-pyrazol-1-yl)-benzenesulfonamide

Procedure

From the reaction of N-tert.-butyl-4-hydrazinobenzenesulfonamide and ethylbutyrylacetate, N-tert.-Butyl-4-(4,5-dihydro-3-propyl-5-oxo-1H-pyrazol-1-yl)-benzenesulfonamide is obtained. Subsequent reaction with 2-ethoxyaniline yields N-tert-butyl-4-(4-(2-ethoxyanilinomethylen)-4,5-dihydro-3-propyl-5-oxo-1H-pyrazol-1-yl)-benzenesulfonamide, Mp: 254° C.

Sources & evidence

ORD record: ord-d0d29fe193134668b776476ff7bae29c
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06034099

Reaction notes

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