4-Bromophenylhydrazine → 2-(4-bromophenyl)-2,4-dihydro-5-propyl-3H-Pyrazol-3-one

HRID 1636342Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.[CH2:10]([CH2:12][CH2:13][CH2:14][C:15](CC([O-])=O)=[O:16])[CH3:11]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:15](=[O:16])[CH2:14][C:13]([CH2:12][CH2:10][CH3:11])=[N:9]2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 121584-Bromophenylhydrazine

HCID 178046443-Oxooctanoate

Product 1

HCID 187617922-(4-bromophenyl)-2,4-dihydro-5-propyl-3H-Pyrazol-3-one

Procedure

From the reaction of 4-bromophenylhydrazine and ethylbutyrylacetate, 2-(4-bromphenyl)-2,4-dihydro-5-propyl-3H-pyrazol-3-one is obtained. Subsequent reaction with 2-ethylaniline yields 2-(4-bromophenyl)-4-(2-ethylanilinomethylene)-2,4-dihydro-5-propyl-3H-pyrazol-3-one, Mp.: 126.9° C.

Sources & evidence

ORD record: ord-42715bdf3e4c451eb377e55abc8398ba
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06034099

Reaction notes

Loading…