HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → 3-methyl-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Product | 3-methyl-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one | HCID 667652 | — |
Reaction Steps
From the reaction of 2-pyridylhydrazine and ethylacetoacetate, 2,4-dihydro-5-methyl-2-(2-pyridyl)-3H-pyrazol-3-one is obtained. Subsequent reaction with 2-ethylaniline yields 4-(2-ethylanilinomethylene)-2,4-dihydro-5-methyl-2-(2-pyridyl)-3H-pyrazol-3-one, Mp 182.9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034099 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-70a3586652d64a4b922395fd5e505443 |
| Source note | uspto-grants-2000_03 |