HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 19351525, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1-(2-chlorophenyl)methyl-5-hydroxymethyl-2-propylthio-1H-imidazole | HCID 15280945 | — |
| Product | HCID 19351525 | HCID 19351525 | 94% |
Reaction Steps
A mixture of 1-(2-chlorophenyl)methyl-5-hydroxymethyl-2-propylthio-1H-imidazole (0.117 g, 0.393 mmol) in thionyl chloride (1 mL) was refluxed for 2 hours, evaporated in vacuo to an amorphous solid and triturated with ether to provide 1-(2-chlorophenyl)methyl-5-chloromethyl-2-propylthio-1H-imidazole hydrochloride (0.13 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034114 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-7e0049cfb8de44a0928a7ac23a20da90 |
| Source note | uspto-grants-2000_03 |