HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylbutylamine → 6-bromo-4-(butylmethylamino)-3-propyl-2H-1-benzopyran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylbutylamine | HCID 8068 | — |
| Reactant | 6-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one | HCID 19351628 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-bromo-4-(butylmethylamino)-3-propyl-2H-1-benzopyran-2-one | HCID 19351644 | — |
Reaction Steps
A solution of 6-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one (0.4 g) and N-methylbutylamine (3 ml) in dimethylformamide (2 ml) was heated under reflux for 30 minutes and then allowed to cool overnight. Evaporation followed by column chromatography yielded 6-bromo-4-(butylmethylamino)-3-propyl-2H-1-benzopyran-2-one, as an oil. (compound 18).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034121 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-c8df5447ccbe4b21b9092117527e3403 |
| Source note | uspto-grants-2000_03 |