Ethylenediamine → HCID 18783142, compound

Participants

Reaction Steps

A solution of 3,3,5,5-tetramethylcyclohexanone (2-13) (1.54 g, 10 mmol) and ethylenediamine (60 mg) in nitromethane (45 ml) was refluxed in argon atmosphere for 25 h. Excess of nitromethane was then removed in vacuo and the residue was purified by flash chromatography on silica gel, eluting with hexane--ethyl acetate (6:1). 1.2 g (61%) of 6 was obtained as an oil.

Provenance & Evidence