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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 163655Generated: October 25, 2026

Dimethylformamide → Tert-butyl 5-[2-acetamido-3-[3-(2,2-difluoroethoxy)phenyl]-1-hydroxypropyl]-2-[(1-methylcyclopentyl)methoxy]morpholine-4-carboxylate

https://huagongshe.com/reaction/163655

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
Reactant2-Bromo-1,1-difluoroethaneHCID 136186—
ReactantTert-butyl 5-[2-acetamido-1-hydroxy-3-(3-hydroxyphenyl)propyl]-2-[(1-methylcyclopentyl)methoxy]morpholine-4-carboxylateHCID 77514712—
ProductTert-butyl 5-[2-acetamido-3-[3-(2,2-difluoroethoxy)phenyl]-1-hydroxypropyl]-2-[(1-methylcyclopentyl)methoxy]morpholine-4-carboxylateHCID 72477973—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-c391dd804744427ab0528370cf0ffd19
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)