2-(4-Aminophenyl)-6-methylbenzothiazole → 2-Bromo-4-(6-methyl-2-benzothiazolyl)benzenamine

Participants

Reaction Steps

2-(4'-Aminophenyl)-6-methylbenzothiazole (0.6 g, 2.5 mmol) was treated with bromine (0.403 g, 2.5 mmol) in dichloromethane according to the above-described general procedure for bromination. Crude product was purified by flash chromatography on silica gel, using ethyl acetate-hexane (1:3) as eluent, to give brown small crystals (0.68 g, 85.3%), m.p. 187.9-189.5° C.

Provenance & Evidence