HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- → HCID 10672270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- | HCID 10131191 | — |
| Reactant | 1-[4-(1H-1-pyrazolyl)phenyl]-2(1H,3H)-imidazolone | HCID 10537222 | — |
| Product | HCID 10672270 | HCID 10672270 | — |
Reaction Steps
(2R,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane was reacted with 1-[4-(1H-1-pyrazolyl)phenyl]-2(1H,3H)-imidazolone in the same manner as in Working Example 11 to give 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-pyrazolyl)phenyl]-2(1H,3H)-imidazolone (Compound 15).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034248 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-6178ed47c26a4df181756659099d77de |
| Source note | uspto-grants-2000_03 |