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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1636707Generated: October 31, 2026

1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- → HCID 3002956, compound

https://huagongshe.com/reaction/1636707

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)-HCID 10131191—
Reactant4-[4-(2H-2-tetrazolyl)phenyl]-3(2H,4H)-1,2,4-triazoloneHCID 10680905—
ProductHCID 3002956HCID 3002956—

Reaction Steps

(2R,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane was reacted with 4-[4-(2H-2-tetrazolyl)phenyl]-3(2H,4H)-1,2,4-triazolone in the same manner as in Working Example 11 to give 2-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-[4-(2H-2-tetrazolyl)phenyl]-3(2H,4H)-1,2,4-triazolone (Compound 25).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06034248
Source datasetuspto-grants-2000_03
ORD IDord-4ccb11199bd440d1a06d9d2e2e5ea09c
Source noteuspto-grants-2000_03