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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1636715Generated: October 30, 2026

1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- → HCID 3002958, compound

https://huagongshe.com/reaction/1636715

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)-HCID 10131191—
ReactantHCID 10681558HCID 10681558—
ProductHCID 3002958HCID 3002958—

Reaction Steps

(2R,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane was reacted with 1-[4-(2-methyl-4-oxazolyl)phenyl]-2(1H,3H)-imidazolone in the same manner as in Working Example 11 to give 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(2-methyl-4-oxazolyl)phenyl]-2(1H,3H) -imidazolone (Compound 37).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06034248
Source datasetuspto-grants-2000_03
ORD IDord-48ddf7f86d5a4ca78651c1d95bc8b002
Source noteuspto-grants-2000_03