HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → Benzo[b]thiophene-2-sulfonic acid [1-(4-amino-3-cyanobenzyl)-2-oxo-pyrrolidin-3-(S)-yl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 1-Benzothiophene-2-sulfonyl chloride | HCID 2776333 | — |
| Reactant | 4-amino-3-(3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)benzonitrile dihydrochloride | HCID 22883631 | — |
| Product | Benzo[b]thiophene-2-sulfonic acid [1-(4-amino-3-cyanobenzyl)-2-oxo-pyrrolidin-3-(S)-yl]amide | HCID 53897651 | — |
Reaction Steps
The title compound (0.131 g, 0.307 mmol) is prepared as in EXAMPLE 1, Part E from 4-amino-3-(3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)benzonitrile dihydrochloride (0.135 g, 0.445 mmol) and benzo[b]thiophene-2-sulfonyl chloride (0.114 g, 0.49 mmol) in acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034093 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-3f1a136b5efa48f0a75c17e10b2c8384 |
| Source note | uspto-grants-2000_03 |