2-Aminophenol → HCID 10904161, compound

Participants

Reaction Steps

28.2 g (0.12 mol) of 1-(2-ethylhexyl)-2-trichloromethylbenzimidazole (prepared by reacting N-2-ethylhexyl-o-phenylenediamine with trichloroacetamido methyl ester), 13.1 g (0.12 mol) of o-aminophenol and 39.4 g (0.38 mol) of triethylamine in 150 ml of ethanol are stirred at room temperature for 15 hours. The ethanol is subsequently removed on a rotary evaporator, ethyl acetate is added to the residue which remains, and the mixture is washed with water and dried over sodium sulfate. 35% of product is identified by HPLC in the product mixture thus obtained; isolation can be carried out, for example, by column chromatography.

Provenance & Evidence