HRID1637040

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5463127

2-Methyl-2-propanyl (2E)-2-butenoate

C8H14O2

结构：C[C@H](N[C@@H](CC(=O)OC(C)(C)C)c1ccccc1)c1ccccc1

HCID15344490

未命名化合物

HCID53938938

tert-Butyl 4-methylpent-2-enoate

C10H18O2

结构：C=CCN([C@@H](C=Cc1ccccc1)CC(=O)OC(C)(C)C)[C@@H](C)c1ccccc1

HCID86755224

未命名化合物

结构：C=CCN([C@@H](C=CC)CC(=O)OC(C)(C)C)[C@@H](C)c1ccccc1

HCID86755229

未命名化合物

PRODUCTS

生成物

结构：CC[C@@H](CC(=O)OC(C)(C)C)N[C@@H](C)c1ccccc1

HCID86755228

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6212

Chloroform

CHCl3

2 次

PROCEDURE

实验过程

The title compound (31) was prepared from compound (10) of Example 3 using the above-described procedure. [α]D21 -54.0 (c 1.81, CHCl3); νmax (CHCl3)/cm-1 1724 s (C=O); δH (300 MHz; CDCl3) 7.36-7.20 (5H, m, Ph), 3.91 (1H, q, J=6.5, PhCHCH3), 2.68 (1H, m, NCHCH2), 2.39, 2.28 (2H, ABX system, JAB =14.3, JAX =5.7, JBX =5.5, CH2CO), 1.47 (9H, s, (CH3)3C), 1.41 (2H, m, CH3CH2), 1.34 (3H, d, J=6.5, PhCHCH3), 0.85 (3H, t, J=7.3, CH3CH2); δC (50 MHz; CDCl3) 172.19 (C=O), 146.44, (Ph:Cipso), 128.53, 126.92 (Ph:Cortho, Cmeta), 126.84 (Ph:Cpara), 80.23 (C(CH3)3), 55.01, 53.71 (CHN), 39.10 (CH2CO), 28.04 (C(CH3)3), 27.78 (CH3CH2), 24.80 (NCHCH3), 10.24 (CH3CH2); m/z (CI) 278 (MH+, 100%), 248 (5), 222 (30), 192 (12), 162 (15), 105 (20); (Found: C, 73.84; H, 10.11; N, 4.93. C17H27NO2 requires C, 73.61; H, 9.81; N, 5.05%).