HCID 21187685, compound → HCID 21967439, compound

HRID 1637089Notes

Reaction equation

HRID 1637089 reaction equation
[ClH:1].Cl.[NH2:3][C@@H:4]1[CH2:8][CH2:7][N:6]([CH:9]2[CH2:14][CH2:13][C:12]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)([OH:15])[CH2:11][CH2:10]2)[CH2:5]1.[N+](C1C=CC([O:32][C:33]([N:35]2[CH:39]([C:40]3[CH:45]=[CH:44][C:43]([F:46])=[C:42]([F:47])[CH:41]=3)[CH:38]([CH:48]3[CH2:50][CH2:49]3)[O:37][C:36]2=[O:51])=O)=CC=1)([O-])=O>>[ClH:1].[F:22][C:19]1[CH:18]=[CH:17][C:16]([C:12]2([OH:15])[CH2:11][CH2:10][CH:9]([N:6]3[CH2:7][CH2:8][C@@H:4]([NH:3][C:33]([N:35]4[C@@H:39]([C:40]5[CH:45]=[CH:44][C:43]([F:46])=[C:42]([F:47])[CH:41]=5)[C@H:38]([CH:48]5[CH2:50][CH2:49]5)[O:37][C:36]4=[O:51])=[O:32])[CH2:5]3)[CH2:14][CH2:13]2)=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 21187685HCID 21187685, compoundHCID 69980981HCID 69980981, compound

Product 1

HCID 21967439HCID 21967439, compound

Procedure

This compound was prepared from the product of Example 35, Step D and the product of Example 43, Step C by a procedure similar to that described in Example 25, Step E. ##STR87##

Sources & evidence

ORD record
ord-f157e38519904df1823f251f51e37b94
Source dataset
uspto-grants-2000_03
Patent number
US06037354

Reaction notes

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