Sodium Hydroxide → HCID 14798434, compound

HRID 1637214Notes

Reaction equation

HRID 1637214 reaction equation
[CH3:1][C:2]1([CH3:22])[CH:11](O)[CH:10]([S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:20]#[N:21])[CH:8]=2)[O:3]1.[OH-].[Na+]>O1CCOCC1>[CH3:1][C:2]1([CH3:22])[CH:11]=[C:10]([S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:20]#[N:21])[CH:8]=2)[O:3]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14798424HCID 14798424, compound

Product 1

HCID 14798434HCID 14798434, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 10 g of 2,2-dimethyl-4-(2-pyridylthio)-6-cyano-3-chromanol, 3 g of sodium hydroxide and 350 ml of dioxane is boiled for 20 minutes. The mixture is cooled and filtered, the filtrate is evaporated and 2,2-dimethyl-4-(2-pyridylthio)-6-cyano-3-chromene, m.p. 110-112°, is obtained.

Workup

  1. temperatureThe mixture is cooled
  2. filtrationfiltered
  3. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-54c772b3363f45bf92d874feacfba173
Source dataset
uspto-grants-2000_03
Patent number
US06040308

Reaction notes

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