Ethyl Acetate → 5-[N-(2-aminobenzoyl)amino]-2-phenyl-1,3,4,5-tetrahydrobenz[cd]indole

Participants

Reaction Steps

A portion (250 mg) of the compound obtained in Example 128 was suspended in methanol (50 ml) and to the suspension was added 10% palladium-carbon (25 mg). The mixture was stirred for 3.5 hours at room temperature under a hydrogen atmosphere. Ethyl acetate was added to the reaction mixture, the catalyst was filtered off and the filtrate was concentrated under reduced pressure. The residue was crystallized from ether to yield 134 mg (58%) of the titled compound.

Provenance & Evidence