HCID 19348362, compound → HCID 19348296, compound

Participants

Reaction Steps

A portion (0.83 g) of the compound obtained in Example 166 was dissolved in methylene chloride (80 ml) and to the solution was added active manganese dioxide (1.66 g). The mixture was heated to reflux for 28 hours. The manganese dioxide was filtered off and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (methylene chloride/methanol=7:1) to yield 240 mg (29%) of the titled compound.

Provenance & Evidence