反应详情

温度

25 °C

To a solution of SnCl2.2H2O (0.5 g, 2.2 mmol) in 5 mL of HCl was added 5-nitro-7-bromobenzothiazole (82 mg, 0.32 mmol) in a portion and the resulting reaction mixture was stirred for 1 h at 25° C. The reaction mixture was basified with aq. NaOH and extracted with EtOAc. Organic extracts were dried over Na2SO4 and concentrated in vacuo to yield 70 mg (31 mmol, 96%) of the desired product.

1. customthe resulting reaction mixture
2. extractionextracted with EtOAc
3. dry with materialOrganic extracts were dried over Na2SO4
4. concentrationconcentrated in vacuo