HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyramide → N-[2-t-Butyl-5-(2-methylpropanoyl)aminocarbonylphenyl)-3-(2,4-dimethoxyphenyl)octanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyramide | HCID 68424 | — |
| Reactant | HCID 19348635 | HCID 19348635 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-[2-t-Butyl-5-(2-methylpropanoyl)aminocarbonylphenyl)-3-(2,4-dimethoxyphenyl)octanamide | HCID 19348528 | — |
Reaction Steps
Following a similar procedure to that described in Example 139, but using N-(2-t-butyl-5-carboxyphenyl)-3-(2,4-dimethoxyphenyl)octanamide (prepared as described in Preparation 7) and 2-methylpropanamide, the title compound was obtained as crystals, melting at 157-159° C. (from acetonitrile).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06040339 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-87738f4b0d284ba095ceb1034339788f |
| Source note | uspto-grants-2000_03 |