Propionamide → HCID 19348419, compound

HRID 1637465Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11](O)=[O:12])=[CH:7][C:6]=1[NH:14][C:15](=[O:33])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][C:24]=1[O:31][CH3:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:4])([CH3:3])[CH3:2].[C:34]([NH2:38])(=[O:37])[CH2:35][CH3:36]>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]([NH:38][C:34](=[O:37])[CH2:35][CH3:36])=[O:12])=[CH:7][C:6]=1[NH:14][C:15](=[O:33])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][C:24]=1[O:31][CH3:32])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:3])([CH3:2])[CH3:4]

Participants

Reactant 2

HCID 6578Propionamide

HCID 19348635HCID 19348635, compound

Product 1

HCID 19348419HCID 19348419, compound

Procedure

Following a similar procedure to that described in Example 139, but using N-(2-t-butyl-5-carboxyphenyl)-3-(2,4-dimethoxyphenyl)octanamide (prepared as described in Preparation 7) and propanamide, the title compound was obtained as crystals.

Sources & evidence

ORD record: ord-b145150f32e24b06a269ded2c60c0ab2
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06040339

Reaction notes

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