Morpholine → HCID 19348420, compound

HRID 1637471Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11](O)=[O:12])=[CH:7][C:6]=1[NH:14][C:15](=[O:31])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[O:29][CH3:30])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:4])([CH3:3])[CH3:2].[NH:32]1[CH2:37][CH2:36][O:35][CH2:34][CH2:33]1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]([N:32]2[CH2:37][CH2:36][O:35][CH2:34][CH2:33]2)=[O:12])=[CH:7][C:6]=1[NH:14][C:15](=[O:31])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[O:29][CH3:30])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:2])([CH3:3])[CH3:4]

Participants

Reactant 2

HCID 8083Morpholine

HCID 19348546HCID 19348546, compound

Product 1

HCID 19348420HCID 19348420, compound

Procedure

Following a similar procedure to that described in Example 8, but using N-(2-t-butyl-5-carboxyphenyl)-3-(2-methoxyphenyl)octanamide (prepared as described in Preparation 74F) and morpholine, the title compound was obtained as a colorless foam-like substance.

Sources & evidence

ORD record: ord-3ab5fc9f9a5b4c8696f50e93adcee568
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06040339

Reaction notes

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