Aminopyrazine → HCID 53655913, compound

HRID 1637481Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]([OH:13])=O)=[CH:7][C:6]=1[NH:14][C:15](=[O:35])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[C:25]([O:31][CH3:32])[C:24]=1[O:33][CH3:34])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:4])([CH3:3])[CH3:2].[NH2:36][C:37]1[CH:42]=[N:41][CH:40]=[CH:39][N:38]=1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11](=[O:13])[NH:36][C:37]2[CH:42]=[N:41][CH:40]=[CH:39][N:38]=2)=[CH:7][C:6]=1[NH:14][C:15](=[O:35])[CH2:16][CH:17]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[C:25]([O:31][CH3:32])[C:24]=1[O:33][CH3:34])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])([CH3:3])([CH3:4])[CH3:2]

Participants

Reactant 2

HCID 78747Aminopyrazine

HCID 19348814HCID 19348814, compound

Product 1

HCID 53655913HCID 53655913, compound

Procedure

Following a similar procedure to that described in Example 8, but using N-(2-t-butyl-5-carboxyphenyl)-3-(2,3,4-trimethoxyphenyl)octanamide (prepared as described in Preparation 74A) and 2-aminopyrazine, the title compound was obtained as a colorless foam-like substance.

Sources & evidence

ORD record: ord-15ef601eb0fe4943ba058335ba3ffde6
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06040339

Reaction notes

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