HCID 19348712, compound → HCID 19348458, compound

HRID 1637503Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[O:12])=[CH:7][C:6]=1[NH:13][C:14](=[O:32])[CH2:15][CH:16]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([O:28][CH3:29])[C:23]=1[O:30][CH3:31])[CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])([CH3:4])([CH3:3])[CH3:2].C([O:35]CC)C.CCCCCC>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]([OH:35])=[O:12])=[CH:7][C:6]=1[NH:13][C:14](=[O:32])[CH2:15][CH:16]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([O:28][CH3:29])[C:23]=1[O:30][CH3:31])[CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])([CH3:2])([CH3:3])[CH3:4]

Participants

Reactant 2

HCID 19348712HCID 19348712, compound

HCID 21584099Diethylether hexane

Product 1

HCID 19348458HCID 19348458, compound

Procedure

Following a procedure similar to that described in Preparation 21, but using N-(2-t-butyl-5-formylphenyl)-3-(2,3-dimethoxyphenyl)octanamide (prepared as described in Preparation 24) as a starting material, the title compound was obtained as crystals, melting at 146-147° C. (from diethyl ether-hexane).

Workup

customthat described in Preparation 21

Sources & evidence

ORD record: ord-6d1cdc25bfc749b28020c109a7713203
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06040339

Reaction notes

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