2-t-Butyl-5-cyano-1-nitrobenzene → Benzonitrile, 3-amino-4-(1,1-dimethylethyl)-

HRID 1637507Notes

Reaction equation

HRID 1637507 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[N:12])=[CH:7][C:6]=1[N+:13]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>CCCCCC.C(OCC)(=O)C>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[N:12])=[CH:7][C:6]=1[NH2:13])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 107033622-t-Butyl-5-cyano-1-nitrobenzene

Product 1

HCID 10702388Benzonitrile, 3-amino-4-(1,1-dimethylethyl)-

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

2-t-Butyl-5-cyano-l-nitrobenzene [prepared as described in step (i) above] was reduced in a similar manner to that described in Preparation 5 to give the title compound as crystals, melting at 94.5-95° C. (from hexane-ethyl acetate).

Workup

  1. customdescribed in Preparation 5

Sources & evidence

ORD record
ord-3974dfabb626470288ce3ca007f44db7
Source dataset
uspto-grants-2000_03
Patent number
US06040339

Reaction notes

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