3-(2,4-Dimethoxyphenyl)heptanoic acid → 3-(2,4-Dimethoxyphenyl)-5-methylhexanoic acid

HRID 1637523Notes

Reaction equation

HRID 1637523 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH:11]([CH2:16][CH2:17][CH2:18]C)[CH2:12][C:13]([OH:15])=[O:14].[CH2:20]([Mg]Br)C(C)C>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH:11]([CH2:16][CH:17]([CH3:18])[CH3:20])[CH2:12][C:13]([OH:15])=[O:14]

Participants

3

Reactant 2

HCID 193485383-(2,4-Dimethoxyphenyl)heptanoic acidHCID 178418816HCID 178418816, compound

Product 1

HCID 193484213-(2,4-Dimethoxyphenyl)-5-methylhexanoic acid

Procedure

Following a similar procedure to that described in Preparation 42a, but using isobutylmagnesium bromide instead of butylmagnesium bromide, the title compound was obtained as an oily substance.

Sources & evidence

ORD record
ord-6c6f482f871440d7b2b54b07715b86f6
Source dataset
uspto-grants-2000_03
Patent number
US06040339

Reaction notes

Loading…