2-Aminomethyl-1-ethylpyrrolidine → HCID 70254927, compound

HRID 1637592Notes

Reaction equation

HRID 1637592 reaction equation
[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([OH:18])=O)=[CH:14][CH:13]=1)/[CH:2]=[C:3](\[CH2:5][CH2:6][CH:7]=[C:8]([CH3:10])[CH3:9])/[CH3:4].[NH2:21][CH2:22][CH:23]1[CH2:27][CH2:26][CH2:25][N:24]1[CH2:28][CH3:29]>>[CH2:28]([N:24]1[CH2:25][CH2:26][CH2:27][CH:23]1[CH2:22][NH:21][C:16](=[O:18])[C:15]1[CH:14]=[CH:13][C:12]([O:11][CH2:1]/[CH:2]=[C:3](\[CH2:5][CH2:6][CH:7]=[C:8]([CH3:9])[CH3:10])/[CH3:4])=[CH:20][CH:19]=1)[CH3:29]

Participants

3

Reactant 2

HCID 1172952-Aminomethyl-1-ethylpyrrolidineHCID 18799494HCID 18799494, compound

Product 1

HCID 70254927HCID 70254927, compoundYield 30%

Procedure

In a manner identical to Example 15, 4-neryloxybenzoic acid(1.64 g) was subjected to a condensation reaction with 2-aminomethyl-1-ethylpyrrolidine (0.84 ml), thereby yielding 0.69 g(30%) of the aimed compound.

Sources & evidence

ORD record
ord-58aade7ecf0c4e099846b289858b973f
Source dataset
uspto-grants-2000_03
Patent number
US06043243

Reaction notes

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